Comprehensive Reconstruction and Visualization of Non-Coding Regulatory Networks in Human
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چکیده
منابع مشابه
Comprehensive Reconstruction and Visualization of Non-Coding Regulatory Networks in Human
Research attention has been powered to understand the functional roles of non-coding RNAs (ncRNAs). Many studies have demonstrated their deregulation in cancer and other human disorders. ncRNAs are also present in extracellular human body fluids such as serum and plasma, giving them a great potential as non-invasive biomarkers. However, non-coding RNAs have been relatively recently discovered a...
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Being a well-characterized pathway, JAK-STAT signaling serves as a valuable paradigm for studying the architecture of gene regulatory networks. The discovery of untranslated or non-coding RNAs, namely microRNAs and long non-coding RNAs, provides an opportunity to elucidate their roles in such networks. In principle, these regulatory RNAs can act as downstream effectors of the JAK-STAT pathway a...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2014
ISSN: 2296-4185
DOI: 10.3389/fbioe.2014.00069